Preferred Label : Anti-STEAP1 CAR T-cells;
NCIt synonyms : STEAP1-targeting CAR T-cells; Anti-STEAP1 CAR-T Cells; Anti-STEAP1 CAR T Cells; STEAP1 CAR-T Cells;
NCIt definition : A preparation of T-lymphocytes that have been genetically modified to express a chimeric
antigen receptor (CAR) targeting the tumor-associated antigen (TAA) six transmembrane
epithelial antigen of the prostate 1 (STEAP1), with potential immunostimulating and
antineoplastic activities. Upon administration, anti-STEAP1 CAR T-cells recognize
and bind to STEAP1-expressing tumor cells, thereby inducing selective toxicity in
STEAP1-expressing tumor cells. STEAP1 is overexpressed in a variety of cancer cell
types.;
NCI Metathesaurus CUI : CL1922096;
Origin ID : C202957;
UMLS CUI : C5908871;
Semantic type(s)
- concept_is_in_subset
- has_target
