NCIt definition : A spectrum of T-cell lymphoproliferative disorders that arise from the oral mucosa
and are characterized by the presence of CD30-positive neoplastic lymphoid cells with
pleomorphic nuclei and abundant cytoplasm. Cells that resemble the hallmark cells
of anaplastic large cell lymphoma are often seen. The lesions arise from the gingiva,
buccal mucosa, tongue, and palate. Patients usually present with a mass that is often
ulcerated. In most cases complete remission is achieved, following excision, with
or without radiotherapy, and with or without systemic chemotherapy.;