Preferred Label : CD33-specific CAR Lentiviral Vector-transduced Allogeneic T-lymphocytes;
NCIt synonyms : Allogeneic Anti-CD33 Chimeric Antigen Receptor T Cells; Allogneic Anti-CD33 CAR-T Cells; Allogeneic CD33-CAR-T Cells;
NCIt definition : A preparation of allogeneic T-lymphocytes transduced with a lentiviral vector expressing
a chimeric antigen receptor (CAR) specific for the CD33 antigen, with potential immunomodulating
and antineoplastic activities. Upon administration, CD33-specific CAR lentiviral vector-transduced
allogeneic T-lymphocytes target and induce selective toxicity in CD33-expressing tumor
cells. CD33 is expressed on normal non-pluripotent hematopoietic stem cells and on
myeloid leukemia cells.;
NCI Metathesaurus CUI : CL1921506;
Origin ID : C202648;
UMLS CUI : C5908657;
Semantic type(s)
- Cell [UMLS semantic type]
- concept_is_in_subset
- has_target
