Preferred Label : Basket Trial Design;
NCIt definition : A type of trial design under a master protocol designed to test a single investigational
drug or drug combination in different populations defined by disease stage, histology,
number of prior therapies, genetic or other biomarkers, or demographic characteristics.
[After US FDA, Master Protocols: Efficient Clinical Trial Design Strategies to Expedite
Development of Oncology Drugs and Biologics Guidance for Industry, 2022];
Alternative definition : CDISC-GLOSS: A type of trial design under a master protocol designed to test a single
investigational drug or drug combination in different populations defined by disease
stage, histology, number of prior therapies, genetic or other biomarkers, or demographic
characteristics. [After US FDA, Master Protocols: Efficient Clinical Trial Design
Strategies to Expedite Development of Oncology Drugs and Biologics Guidance for Industry,
2022] See also master protocol.;
NCI Metathesaurus CUI : CL1921888;
Origin ID : C202580;
UMLS CUI : C5908627;
Semantic type(s)
- concept_is_in_subset
