H-ras Antisense Oligodeoxynucleotide ISIS 2503

Preferred Label : H-ras Antisense Oligodeoxynucleotide ISIS 2503;

NCIt synonyms : H-RAS Antisense;

NCIt related terms : ISIS 2503; ISIS-2503;

NCIt definition : A synthetic oligodeoxynucleotide. Functioning as an anti-sense agent, it hybridizes to the translation initiation region of the human mRNA for the oncogene H-Ras. ISIS 2503 selectively inhibits the expression of H-Ras, and may inhibit the growth of some Ras-dependent tumor cells. (NCI04);

Alternative definition : NCI-GLOSS: A substance that is being studied in the treatment of cancer.;

UNII : I444I66XWH;

CAS number : 149957-14-2;

Molecule name : ISIS-2503; ISIS 2503;

NSC code : 718878;

Codes from synonyms : CDR0000044857;

Details

Origin ID

C2024;

UMLS CUI

C0879385;

Currated CISMeF NLP mapping
- ISIS 2503 [MeSH concept]
- ISIS 2503 [MeSH Supplementary Concept]
Semantic type(s)
- Nucleic Acid, Nucleoside, or Nucleotide [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- ISIS 2503 [MeSH concept]
- ISIS 2503 [MeSH Supplementary Concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
is_component_of_chemotherapy_regimen
- Gemcitabine/ISIS 2503 [NCIt concept]

Keyword's position in hierarchy(ies) :

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