Ceftobiprole - CISMeF

Preferred Label : Ceftobiprole;

NCIt definition : A broad-spectrum, fifth-generation, pyrrolidinone cephalosporin with antibacterial activity. Ceftobiprole binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.;

UNII : 5T97333YZK;

CAS number : 209467-52-7; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 209467-52-7 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : RO 63-9141; BAL9141;

Chemical formula : C20H22N8O6S2;

Details

Origin ID

C65306;

UMLS CUI

C1100584;

CISMeF manual mappings
- ceftobiprole [International Nonproprietary Name]
Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Ceftobiprole [LOINC component]
- Ceftobiprole (substance) [SNOMED CT concept]
- ceftobiprole [International Nonproprietary Name]
- ceftobiprole [MeSH concept]
- ceftobiprole [MeSH Supplementary Concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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