Preferred Label : B. infantis-based Formulation PBCLN-014;
NCIt synonyms : Bifidobacterium longum Subspecies infantis-based Formulation PBCLN-014;
NCIt definition : An orally bioavailable formulation containing the naturally occurring lactic acid-producing
gut bacteria Bifidobacterium longum subspecies infantis (B. infantis), with potential
immunomodulating activity. Upon oral administration, B. infantis-based formulation
PBCLN-014 may restore the unhealthy, altered gut microbiome, enhance the microbial
diversity and function in the gastrointestinal (GI) tract and may re-establish a healthy
microbiome in the GI tract. This may improve intestinal barrier function, suppress
inflammation, enhance the patients' immunological activity and lower the risk of GI
antibiotic-resistant bacterial infections, bacteremia and graft-versus-host disease
(GvHD) in patients undergoing solid organ and allogeneic stem cell transplantation.;
Molecule name : PBCLN-014; PBCLN 014;
NCI Metathesaurus CUI : CL1921181;
Origin ID : C202210;
UMLS CUI : C5907946;
Semantic type(s)
concept_is_in_subset