Transformed EGFR-Positive Lung Adenocarcinoma to Small Cell Carcinoma

Preferred Label : Transformed EGFR-Positive Lung Adenocarcinoma to Small Cell Carcinoma;

NCIt synonyms : Transformed EGFR-Positive Lung Adenocarcinoma to Lung Small Cell Carcinoma;

NCIt definition : Histologic transformation of EGFR mutation-positive lung adenocarcinoma to small cell carcinoma, following treatment with tyrosine kinase inhibitors.;

Neoplastic status : Malignant;

NCI Metathesaurus CUI : CL1921156;

Details

Origin ID

C202133;

UMLS CUI

C5908360;

Disease excludes abnormal cell
- Malignant Epithelial Small Cell [NCIt concept]
- Malignant Squamous Cell [NCIt concept]
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
- Neoplastic Squamous Cell [NCIt concept]
Excludes anatomical site(s)
- Neck [NCIt concept]
- Skin [NCIt concept]
Has associated anatomic sites
- Lung [NCIt concept]
- Respiratory System [NCIt concept]
- Thoracic Cavity [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
concept_is_in_subset
- Cellosaurus Disease Terminology [NCIt concept]
- Cellosaurus Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Mixed Neoplastic Glandular and Squamous Cell Population [NCIt concept]
- Premalignant Lesion [NCIt concept]
disease_has_abnormal_cell
- Adenocarcinoma Cell [NCIt concept]
- Malignant Cell [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Malignant Neuroendocrine Small Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Glandular Cell [NCIt concept]
disease_has_finding
- Carcinomatous Component Present [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Transformed Phase of Disease [NCIt concept]
disease_has_molecular_abnormality
- EGFR Gene Mutation [NCIt concept]
disease_has_normal_cell_origin
- Epithelial Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Lung [NCIt concept]
disease_mapped_to_gene
- ALK Gene [NCIt concept]
- EGFR Gene [NCIt concept]
- EML4/ALK Fusion Gene [NCIt concept]
- KRAS Gene [NCIt concept]
- TP53 Gene [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Gain of Chromosome 1q [NCIt concept]
- Gain of Chromosome 20q [NCIt concept]
- Gain of Chromosome 3q24-qter [NCIt concept]
- Gain of Chromosome 5p [NCIt concept]
- Gain of Chromosome 8q [NCIt concept]
- Loss of Chromosome 13q [NCIt concept]
- Loss of Chromosome 4q [NCIt concept]
- Loss of Chromosome 5q [NCIt concept]
- Loss of Chromosome 6q [NCIt concept]
- Loss of Chromosome 8p [NCIt concept]
- Loss of Chromosome 9 [NCIt concept]
- Loss of Chromosome Y [NCIt concept]
disease_may_have_molecular_abnormality
- KRAS Gene Amplification [NCIt concept]
- LKB1 Gene Inactivation [NCIt concept]
- TP53 Gene Inactivation [NCIt concept]

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