Transformed EGFR-Positive Lung Non-Small Cell Carcinoma to Small Cell Carcinoma

Preferred Label : Transformed EGFR-Positive Lung Non-Small Cell Carcinoma to Small Cell Carcinoma;

NCIt synonyms : Transformed EGFR-Positive Lung Non-Small Cell Carcinoma to Lung Small Cell Carcinoma;

NCIt definition : Histologic transformation of EGFR mutation-positive lung non-small cell carcinoma to small cell carcinoma, following treatment with tyrosine kinase inhibitors.;

Neoplastic status : Malignant;

Details

Origin ID

C202132;

Disease excludes abnormal cell
- Malignant Epithelial Small Cell [NCIt concept]
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
Excludes anatomical site(s)
- Neck [NCIt concept]
- Skin [NCIt concept]
Has associated anatomic sites
- Lung [NCIt concept]
- Respiratory System [NCIt concept]
- Thoracic Cavity [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Premalignant Lesion [NCIt concept]
disease_has_abnormal_cell
- Malignant Cell [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Malignant Neuroendocrine Small Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
disease_has_finding
- Carcinomatous Component Present [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Transformed Phase of Disease [NCIt concept]
disease_has_molecular_abnormality
- EGFR Gene Mutation [NCIt concept]
disease_has_normal_cell_origin
- Epithelial Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Lung [NCIt concept]
disease_mapped_to_gene
- EGFR Gene [NCIt concept]
- TP53 Gene [NCIt concept]
disease_may_have_molecular_abnormality
- TP53 Gene Inactivation [NCIt concept]

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