" /> Allogeneic Anti-CD33 CAR T-cells VCAR33 - CISMeF





Preferred Label : Allogeneic Anti-CD33 CAR T-cells VCAR33;

NCIt synonyms : Donor-Derived Anti-CD33 CAR T Cells VCAR33; Allogeneic Anti-CD33 CAR-T Cells VCAR33;

NCIt definition : A preparation of allogeneic T-lymphocytes, derived from the same matched healthy donor who provided a stem cell transplant and transduced with a lentiviral vector to express a chimeric antigen receptor (CAR) specific for the CD33 antigen, with potential immunomodulating and antineoplastic activities. Upon administration, allogeneic anti-CD33 CAR T-cells VCAR33 specifically recognize and kill CD33-expressing tumor cells. CD33 is expressed on normal non-pluripotent hematopoietic stem cells and is overexpressed on myeloid leukemia cells.;

Molecule name : VCAR 33; VCAR-33;

NCI Metathesaurus CUI : CL1921438;

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30/07/2025


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