NCIt definition : Dipeptidyl aminopeptidase-like protein 6 (865 aa, 98 kDa) is encoded by the human
DPP6 gene. This protein is involved in the modulation of both Kv4 (KCND) family protein
localization and voltage-activated A-type potassium ion channel activity.;
Alternative definition : CDISC: An antigen encoded by the DPP6 gene that binds to and regulates the biophysical
characteristics of voltage-gated potassium channels. It can be considered as an autoantigen
and is commonly associated with autoimmune encephalitis.;
NCIt note : Dipeptidyl aminopeptidase-like protein 6 has no aminopeptidase activity due to the
absence of the conserved serine residue normally present in the catalytic domain of
serine proteases.;