NCIt definition : Human DPP6 wild-type allele is located in the vicinity of 7q36.2 and is approximately
1146 kb in length. This allele, which encodes A-type potassium channel modulatory
protein DPP6, plays a role in the regulation of neuronal excitability mediated by
voltage-activated A-type potassium ion channels. Mutation of the gene is associated
with paroxysmal familial ventricular fibrillation 2 and autosomal dominant intellectual
developmental disorder 33. Polymorphism in this gene may be associated with variable
susceptibility to amyotrophic lateral sclerosis.;