DPP6 wt Allele

Preferred Label : DPP6 wt Allele;

NCIt synonyms : Dipeptidylpeptidase 6 Gene; DPL1; Dipeptidyl Peptidase 6 Gene; DPPX; Dipeptidylpeptidase VI Gene; MRD33; Dipeptidyl-Peptidase 6 Gene; Dipeptidyl Peptidase Like 6 wt Allele; VF2;

NCIt definition : Human DPP6 wild-type allele is located in the vicinity of 7q36.2 and is approximately 1146 kb in length. This allele, which encodes dipeptidyl aminopeptidase-like protein 6, plays a role in the regulation of neuronal excitability mediated by voltage-activated A-type potassium ion channels. Mutation of the gene is associated with paroxysmal familial ventricular fibrillation 2 and autosomal dominant intellectual developmental disorder 33. Polymorphism in this gene may be associated with variable susceptibility to amyotrophic lateral sclerosis.;

NCI Metathesaurus CUI : CL1921395;

GenBank Accession Number : M96859;

Details

Origin ID

C201942;

UMLS CUI

C5890947;

OMIM relation
- Dipeptidyl peptidase VI [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_plays_role_in_process
- Ion Transport Process [NCIt concept]
- Transmembrane Transport [NCIt concept]
- Voltage-Gated Potassium Ion Channel Activation [NCIt concept]

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