Preferred Label : Yeast-derived Beta-glucan Supplement;
NCIt synonyms : Yeast-derived Beta-glucan;
NCIt definition : A dietary supplement composed of yeast-derived beta-glucan, with potential antioxidant,
anti-inflammatory and immunomodulatory activities. Upon administration of yeast-derived
beta-glucan supplement, beta-glucan may decrease both superoxide dismutase and reductase
activities and the release of pro-inflammatory cytokines, thereby reducing oxidative
stress and inflammation. Beta-glucan may also stimulate the immune system by binding
to a lectin site within the complement receptor 3 (CR3 or iC3b receptor) on leukocytes,
priming the receptor to trigger cytotoxic degranulation of leukocytes when leukocyte
CR3 binds to iC3b-opsonized cells. iC3b is the proteolyticly inactive product of the
complement cleavage fragment C3b.;
NCI Metathesaurus CUI : CL1920775;
Origin ID : C201934;
UMLS CUI : C5908254;
Semantic type(s)
- concept_is_in_subset
