Preferred Label : Oncolytic Virus M1-c6v1;
NCIt synonyms : Recombinant Oncolytic Virus M1-c6v1; OV M1-c6v1;
NCIt definition : A mutant variant of the recombinant oncolytic alphavirus M1, with potential antineoplastic
activity. Upon intravenous administration, oncolytic virus M1-c6v1 infects and replicates
in tumor cells causing viral-mediated tumor cell lysis. The released virus particles,
in turn, infect and replicate in neighboring tumor cells. Tumor antigens released
from the lysed tumor cells also activate the immune system to induce a tumor-specific
systemic immune and cytotoxic T-lymphocyte (CTL) response, thereby killing nearby
non-infected tumor cells.;
Molecule name : M1 c6v1; M1-c6v1;
Origin ID : C201915;
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