Preferred Label : Gallium Ga 68 R8760;
NCIt synonyms : Gallium Ga 68-R8760; 68Ga-R8760;
NCIt definition : A radioconjugate composed of a melanocortin 2 receptor (MC2R; adrenocorticotropic
hormone receptor; ACTHR)-binding ligand, conjugated to the radioisotope gallium Ga
68, with potential use as a tracer for MC2R-expressing tumors during positron emission
tomography (PET). Upon administration of gallium Ga 68 R8760, the MC2R-targeting moiety
targets and binds to MC2R-expressing tumor cells. Upon binding, MC2R-expressing tumor
cells can be detected during PET imaging. MC2R, a member of the melanocortin receptor
subfamily of type 1 G protein-coupled receptors, plays a key role in adrenal steroidogenesis
and is overexpressed in adrenocortical carcinoma.;
NCI Metathesaurus CUI : CL1920710;
Origin ID : C201841;
UMLS CUI : C5908206;
Semantic type(s)
- concept_is_in_subset
