Hyalinizing Clear Cell Carcinoma

Preferred Label : Hyalinizing Clear Cell Carcinoma;

NCIt synonyms : HCCC;

NCIt definition : A rare, slow-growing carcinoma characterized by the presence of malignant clear and eosinophilic cells in a hyalinized stroma. It has been described in the salivary glands and lung. Most cases are associated with translocation of EWSR1 and ATF1, resulting in the formation of EWSR1-ATF1 fusion gene. The prognosis is good.;

Neoplastic status : Malignant;

NCI Metathesaurus CUI : CL1777034;

Details

Origin ID

C201821;

UMLS CUI

C5568426;

Disease excludes abnormal cell
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Hyalinizing clear cell carcinoma (morphologic abnormality) [SNOMED CT concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
disease_has_abnormal_cell
- Malignant Cell [NCIt concept]
- Malignant Cell with Eosinophilic Cytoplasm [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Malignant Epithelial Clear Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
disease_has_finding
- Carcinomatous Component Present [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Hyalinized Stroma Formation [NCIt concept]
- Low Grade Lesion [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
disease_has_normal_cell_origin
- Epithelial Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
disease_mapped_to_gene
- EWSR1/ATF1 Fusion Gene [NCIt concept]
disease_may_have_cytogenetic_abnormality
- EWSR1 Gene Rearrangement [NCIt concept]
pathogenesis_of_disease_involves_gene
- EWSR1/ATF1 Fusion Gene [NCIt concept]
- EWSR1/ATF1 Fusion Gene Type 1 [NCIt concept]
- EWSR1/ATF1 Fusion Gene Type 2 [NCIt concept]

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