NCIt synonyms : Alpha 3 Subunit of VLA-3 Receptor Gene; JEB7; Integrin Subunit Alpha 3 wt Allele; Integrin Alpha 3 Gene; Very Late Activation Protein 3 Receptor, Alpha-3 Subunit Gene; MSK18; Integrin, Alpha 3 (Antigen CD49C, Alpha 3 Subunit of VLA-3 Receptor) Gene; Very Late Activation Receptor Subunit Alpha-3 Gene; VLA3a; VCA-2; CD49C; VL3A; GAPB3; Antigen Identified By Monoclonal Antibody J143 Gene; ILNEB; GAP-B3; FRP-2; Integrin, Alpha-3 Gene;
NCIt definition : Human ITGA3 wild-type allele is located in the vicinity of 17q21.33 and is approximately
35 kb in length. This allele, which encodes integrin alpha-3 protein, is involved
in cell-matrix adhesion and invadopodia formation. Mutation of the gene is associated
with junctional epidermolysis bullosa 7 including interstitial lung disease and nephrotic
syndrome.;
OMIM relation