IPO8 wt Allele

Preferred Label : IPO8 wt Allele;

NCIt synonyms : IMP8; VISS; RAN Binding Protein 8 Gene; Importin 8 wt Allele; RANBP8;

NCIt definition : Human IPO8 wild-type allele is located in the vicinity of 12p11.21 and is approximately 67 kb in length. This allele, which encodes importin-8 protein, is involved in nuclear cargo import. Mutation of the gene is associated with vascular aneurysm, immune dysregulation, skeletal anomalies, and skin and joint laxity (VISS) syndrome.;

GenBank Accession Number : U77494;

Details

Origin ID

C201806;

OMIM relation
- Importin 8 [OMIM gene]
gene_found_in_organism
- Human [NCIt concept]
gene_is_element_in_pathway
- Protein Import into Nucleus Pathway [NCIt concept]
gene_plays_role_in_process
- Intracellular Transport [NCIt concept]
- Ligand Binding [NCIt concept]
- Nucleocytoplasmic Transport [NCIt concept]
- Protein-Protein Interaction [NCIt concept]
- Subcellular Protein Targeting [NCIt concept]
- Transport Process [NCIt concept]

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