NCIt synonyms : HBeAg-Binding Protein 2 Binding Protein C Gene; C14orf151; Chromosome 14 Open Reading Frame 151 Gene; C14orf173; Chromosome 14 Open Reading Frame 173 Gene; CMTDIE; pp9484; FSGS5; MGC13251; Inverted Formin 2 wt Allele; Formin, Inverted, 2 Gene; Inverted Formin, FH2 and WH2 Domain Containing Gene;
NCIt definition : Human INF2 wild-type allele is located in the vicinity of 14q32.33 and is approximately
41 kb in length. This allele, which encodes inverted formin-2 protein, plays a role
in cytoskeletal actin filament remodeling. Mutation of the gene is associated with
focal segmental glomerulosclerosis 5 and dominant intermediate Charcot-Marie-Tooth
disease E.;
OMIM relation