SWI/SNF Complex-Deficient Sinonasal Carcinoma

Preferred Label : SWI/SNF Complex-Deficient Sinonasal Carcinoma;

NCIt synonyms : SWI/SNF-Deficient Sinonasal Carcinoma; Sinonasal SWI/SNF-Deficient Carcinoma; Sinonasal SWI/SNF Complex-Deficient Carcinoma;

NCIt definition : A highly aggressive, poorly to undifferentiated carcinoma that arises from the sinonasal tract. It is characterized by loss of one SWI/SNF complex subunit (either SMARCB1 or SMARCA4) and lacks histological features to allow classification into another specific entity. Most patients present with locally advanced disease.;

Neoplastic status : Malignant;

Details

Origin ID

C201634;

Disease excludes abnormal cell
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
Has associated anatomic sites
- Head and Neck [NCIt concept]
- Sinonasal Tract [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
disease_has_abnormal_cell
- Malignant Cell [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
disease_has_finding
- Aggressive Clinical Course [NCIt concept]
- Carcinomatous Component Present [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- SWI/SNF Complex Deficiency [NCIt concept]
disease_has_normal_cell_origin
- Epithelial Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Head and Neck [NCIt concept]
- Sinonasal Tract [NCIt concept]

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