Preferred Label : iPSC-derived MSCs CYP-001;
NCIt synonyms : Induced Pluripotent Stem Cell-derived Mesenchymal Stem Cells CYP-001; Allogeneic MSCs CYP-001;
NCIt definition : A preparation of allogeneic mesenchymal stem cells (MSCs) derived from induced pluripotent
stem cells (iPSCs), with potential immunomodulating activity. iPSCs are derived from
one healthy adult donor and are expanded and differentiated into mesenchymoangioblasts
(MCAs), which are further expanded and cultured, upon which MSCs are formed and further
expanded. Upon intravenous administration and following allogeneic hematopoietic stem
cell transplantation (HSCT), the iPSC-derived MSCs CYP-001 may attenuate and prevent
acute graft versus host disease (aGvHD).;
Molecule name : CYP-001; CYP 001;
NCI Metathesaurus CUI : CL1650269;
Origin ID : C201558;
UMLS CUI : C5401677;
Semantic type(s)
- Cell [UMLS semantic type]
- concept_is_in_subset
