Preferred Label : RSVPreF3/AS01E RSV Vaccine;
NCIt synonyms : Respiratory Syncytial Virus Vaccine, Adjuvanted; RSVPreF3 OA Vaccine; Recombinant Subunit Pre-fusion RSV Glycoprotein Antigen Combined with AS01E; RSV Vaccine RSVPreF3 Plus AS01E; RSVPreF3 Antigen Combined with AS01E; RSVPreF3 Older Adults Vaccine;
CISMeF synonym : 300000025731;
NCIt definition : A respiratory syncytial virus (RSV) vaccine, that can potentially be used for the
active immunization and prevention of lower respiratory tract disease (LRTD) caused
by RSV in individuals 60 years of age and older. The RSVPreF3/AS01E RSV vaccine is
composed of an antigen component, a recombinant RSV glycoprotein F stabilized in pre-fusion
conformation (RSVPreF3), and an adjuvant component, AS01E, which is a liposomal formulation
composed of 3-O-desacyl-4'-monophosphoryl lipid A (MPL) from Salmonella minnesota
and QS-21, a saponin purified from plant extract Quillaja saponaria Molina. Upon reconstitution
of the RSVPreF3 antigen component with the adjuvant AS01E and upon the intramuscular
(IM) administration of the suspension, the RSVPreF3/AS01E RSV vaccine induces an active
immune response against RSVpreF3 and induces neutralizing antibodies against RSV,
thereby protecting against LRTD caused by RSV.;
Drug name : Arexvy;
NCI Metathesaurus CUI : CL1920466;
Origin ID : C201553;
UMLS CUI : C5856889;
Semantic type(s)
- concept_is_in_subset
