NCIt synonyms : Immunoglobulin Heavy Constant Gamma 2 (G2m Marker) wt Allele; IgG2 Heavy Chain Constant Region Gene; Constant Region of Heavy Chain of IgG2 Gene; Immunoglobulin Gamma 2 (Gm Marker) Gene; Immunoglobulin Heavy Constant Gamma 2 (Gm Marker) Gene;
NCIt definition : Human IGHG2 wild-type allele is located in the vicinity of 14q32.33 and is approximately
5 kb in length. This allele, which encodes immunoglobulin heavy constant gamma 2 protein,
plays a role in antigen binding and immunoglobulin receptor binding activities. Mutation
of the gene is associated with selective IgG2 deficiency.;