NCIt synonyms : Myeloma-Overexpressed Gene; OCIM; Oncogene in Multiple Myeloma Gene; Myeloma Overexpressed Gene (in a Subset of t(11;14) Positive Multiple Myelomas) Gene; Myeloma Overexpressed (in a Subset of t(11;14) Positive Multiple Myelomas) Gene; Myeloma Overexpressed wt Allele;
NCIt definition : Human MYEOV wild-type allele is located in the vicinity of 11q13.3 and is approximately
48 kb in length. This allele, which encodes myeloma-overexpressed gene protein, may
be involved in RNA binding. Concomitant overexpression of this gene and the CCND1
gene is associated with both esophageal squamous cell carcinoma characterized by amplifications
at 11q13 and multiple myeloma associated with a chromosomal translocation t(11;14)(q13;q32),
which may juxtapose an IGH locus enhancer with the MYEOV gene.;
OMIM relation