Preferred Label : Lactobacillus vaginalis-containing Vaginal Capsule;
NCIt synonyms : L. vaginalis Vaginal Capsule; Vaginal Capsule Containing Lactobacillus vaginalis; Lactobacillus vaginalis-containing Vaginal Formulation; Lactobacillus vaginalis-containing Capsule; L. vaginalis-containing Vaginal Formulation; Lactobacillus Vaginalis Capsule Formulation;
NCIt definition : A vaginal capsule formulation containing the lactic acid-producing bacterium Lactobacillus
vaginalis (L. vaginalis), with vaginal healing, soothing, protective and immunomodulating
activities. Upon intravaginal application of the L. vaginalis-containing vaginal capsule,
L. vaginalis provides the naturally occurring vaginal bacterium to a dysregulated
vaginal microbiome, and thereby restores the vaginal Lactobacillus flora to an optimal
vaginal lactobacillus-dominated microbiota. L. vaginalis produces efficient levels
of lactic acid, which normalizes and restores a healthy vaginal pH. Altogether, this
enhances epithelial barrier integrity and barrier protection, and may prevent or improve
various vulvovaginal symptoms, such as vulvovaginal atrophy, vaginal dryness, difficulty
with intercourse, genital skin irritation, itching, burning, vaginal pain, bleeding,
increased vaginal discharge and an unpleasant odor. In addition, a healthy vaginal
microbiome provides immunomodulation and may prevent inflammation and infection. L.
vaginalis, normally proliferating in the anaerobic environment of a healthy vagina,
produces various antimicrobial compounds such as lactic acid, hydrogen peroxide (H2O2)
and bacteriocins and maintains vaginal health.;
NCI Metathesaurus CUI : CL1915468;
Origin ID : C201078;
UMLS CUI : C5856618;
Semantic type(s)
- concept_is_in_subset
