Preferred Label : BCR Signaling Pathway Inhibitor DZD8586;
NCIt definition : An inhibitor of the B-cell antigen receptor (BCR) signaling pathway, with potential
antineoplastic activity. Upon administration, BCR signaling pathway inhibitor DZD8586
blocks signaling through the BCR signaling pathway. This prevents the proliferation
of malignant B-cells in which the BCR signaling pathway is overactivated. DZD8586
is able to cross the blood-brain barrier (BBB) and thus potentially useful in the
treatment of central nervous system (CNS) metastases.;
Molecule name : DZD-8586; DZD 8586;
NCI Metathesaurus CUI : CL1915128;
Origin ID : C200855;
UMLS CUI : C5854614;
Semantic type(s)
- concept_is_in_subset
