DNAI1 wt Allele

Preferred Label : DNAI1 wt Allele;

NCIt synonyms : PCD; CILD1; Dynein Axonemal Intermediate Chain 1 wt Allele; DIC1; ICS1; Dynein, Axonemal, Intermediate Polypeptide 1 Gene; Immotile Cilia Syndrome 1 Gene; Dynein, Axonemal, Intermediate Chain 1 Gene;

NCIt definition : Human DNAI1 wild-type allele is located in the vicinity of 9p13.3 and is approximately 64 kb in length. This allele, which encodes dynein axonemal intermediate chain 1 protein, plays a role in dynein-microtubule interactions and force generation in respiratory cilia. Mutation of the gene is associated with primary ciliary dyskinesia 1.;

NCI Metathesaurus CUI : CL1915115;

GenBank Accession Number : AF091619;

Details

Origin ID

C200837;

UMLS CUI

C5848998;

OMIM relation
- Dynein, axonemal, intermediate chain 1 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_is_element_in_pathway
- Amyotrophic Lateral Sclerosis Pathway [NCIt concept]
- Huntington's Disease Pathway [NCIt concept]
gene_plays_role_in_process
- Cell Movement Process [NCIt concept]
- Cytoskeletal Process [NCIt concept]
- Microtubule Process [NCIt concept]
- Regulation of Cell Shape [NCIt concept]
- Tubulin Binding [NCIt concept]

Keyword's position in hierarchy(ies) :

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