Refractory Polycythemia Vera, Post-Polycythemic Myelofibrosis Phase

Preferred Label : Refractory Polycythemia Vera, Post-Polycythemic Myelofibrosis Phase;

NCIt definition : Polycythemia vera, post-polycythemic myelofibrosis phase that is resistant to treatment.;

Neoplastic status : Malignant;

NCI Metathesaurus CUI : CL1915299;

Détails

Origin ID

C200605;

UMLS CUI

C5856330;

Disease excludes abnormal cell
- Segmented Neutrophil [NCIt concept]
Disease excludes normal cell origin
- Bone Marrow Stem Cell Committed to the Megakaryocytic Lineage [NCIt concept]
Disease may have findings
- Chronic Clinical Course [NCIt concept]
- Hemorrhage [NCIt concept]
- Osteosclerosis [NCIt concept]
Has associated anatomic sites
- Bone Marrow [NCIt concept]
- Hematopoietic and Lymphatic System [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
concept_is_in_subset
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
disease_excludes_cytogenetic_abnormality
- Philadelphia Chromosome [NCIt concept]
- t(9;22)(q34.1;q11.2) [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Eosinophilia [NCIt concept]
- Increased Red Cell Mass [NCIt concept]
- Ineffective Hematopoiesis [NCIt concept]
- Neutrophilia [NCIt concept]
- Not Otherwise Specified Lesion [NCIt concept]
disease_excludes_molecular_abnormality
- BCR-ABL1 Fusion Protein Expression [NCIt concept]
disease_has_abnormal_cell
- Dacrocyte [NCIt concept]
- Hyperchromatic Megakaryocyte [NCIt concept]
- Malignant Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Hematopoietic and Lymphoid Cell [NCIt concept]
- Neoplastic Myeloid Cell [NCIt concept]
disease_has_finding
- Bone Marrow Fibrosis [NCIt concept]
- Extramedullary Hematopoiesis [NCIt concept]
- Hepatomegaly [NCIt concept]
- Leukoerythroblastic Reaction [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Poikilocytosis [NCIt concept]
- Refractory Disease [NCIt concept]
- Splenomegaly [NCIt concept]
disease_has_normal_cell_origin
- Bone Marrow Stem Cell [NCIt concept]
- Hematopoietic and Lymphoid Cell [NCIt concept]
- Multipotent Bone Marrow Stem Cell [NCIt concept]
disease_has_normal_tissue_origin
- Hematopoietic Tissue [NCIt concept]
- Hematopoietic and Lymphoid Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Bone Marrow [NCIt concept]
- Hematopoietic and Lymphatic System [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Gain of Chromosome 8 [NCIt concept]
- Gain of Chromosome 9 [NCIt concept]
- Loss of Chromosome 13q [NCIt concept]
- Loss of Chromosome 1p [NCIt concept]
- Loss of Chromosome 20q [NCIt concept]
disease_may_have_molecular_abnormality
- JAK2 Exon 12 Mutation [NCIt concept]
- JAK2 NP_004963.1:p.V617F [NCIt concept]

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