Preferred Label : ALDH2 Activator FP-045;
NCIt synonyms : Aldehyde Dehydrogenase 2 Activator FP-045;
NCIt definition : An orally bioavailable selective activator of the mitochondrial isoform of aldehyde
dehydrogenase (ALDH2), with potential protective activity. Upon oral administration,
ALDH2 activator FP-045 increases ALDH2 activity. This increases the metabolism of
toxic reactive aldehydes and lowers the level of the toxic aldehydes. This may protect
cells from the toxic aldehydes and prevent mitochondria diseases and disorders. ALDH2,
a mitochondrial regulator of toxic aldehyde metabolism, plays an important role in
the metabolism of toxic aldehydes. Toxic aldehydes are produced by oxidative stress.;
Molecule name : FP 045; FP-045;
NCI Metathesaurus CUI : CL1915292;
Origin ID : C200589;
UMLS CUI : C5854572;
Semantic type(s)
- concept_is_in_subset
- has_target
