Preferred Label : Candida Antigen Extract Patch VDMN-21;
NCIt synonyms : Candida Antigen Extract-containing Microneedle Patch VDMN-21; C. albicans Antigen Extract Patch VDMN-21;
NCIt definition : An dissolvable microarray-based formulation containing an extract of Candida albicans
(C. albicans) antigens, with immunomodulatory activity. Upon administration of the
C. albicans antigen extract patch VDMN-21 adjacent to the cutaneous human papilloma
virus (HPV)-infected wart(s), the C. albicans antigens, upon release from the microarray,
stimulate the immune system to mount a cytotoxic T-lymphocyte (CTL)-mediated immune
response against the C. albicans antigens and cause a delayed type hypersensitivity
response against other local antigens, including antigens within the wart tissue.
This leads to the production of Th1 cytokines, and the activation of natural killer
(NK) cell- and CTL- mediated killing of HPV-infected cells. This causes clearing of
both local and distant warts, and prevents HPV infection and wart formation that results
from HPV infection.;
Molecule name : VDMN 21; VDMN-21;
NCI Metathesaurus CUI : CL1907555;
Origin ID : C200555;
concept_is_in_subset
