Preferred Label : Akkermansia muciniphila Probiotic;
NCIt synonyms : A. muciniphila Probiotic; Akkermansia Oncobax (R)- muciniphila;
NCIt definition : An orally bioavailable, probiotic supplement containing Akkermansia muciniphila (A.
muciniphila), a naturally occurring bacterium found in the healthy human gastrointestinal
(GI) tract, with potential immunomodulating and mucosal protective activities. Upon
oral administration of A. muciniphila probiotic, A. muciniphila may help maintain
adequate colonization of the GI tract by modulating the composition of the normal
microflora. During colonization in the GI tract, the bacteria may form a protective
intestinal barrier that may help maintain gut lining and prevent both damage to the
mucosal epithelia caused by toxins and attachment of potential pathogens, thereby
protecting against bacterial translocation and infection. In addition, the probiotic
bacteria may potentiate immunity and may improve response to certain cancer immunotherapies.;
Drug name : Oncobax-AK;
NCI Metathesaurus CUI : CL1907533;
Origin ID : C200541;
UMLS CUI : C5856307;
Semantic type(s)
concept_is_in_subset