Mixed Phenotype Acute Leukemia, T/Megakaryocytic

Preferred Label : Mixed Phenotype Acute Leukemia, T/Megakaryocytic;

NCIt synonyms : MPAL-T/Mk;

NCIt definition : A very rare mixed phenotype acute leukemia in which the blasts show evidence of T-cell and megakaryocytic lineage but are negative for KMT2A rearrangement and t(9;22)(q34;q11.2) translocation.;

Neoplastic status : Malignant;

NCI Metathesaurus CUI : CL1907500;

Details

Origin ID

C200502;

Disease may have findings
- Granulocytopenia [NCIt concept]
- Ineffective Hematopoiesis [NCIt concept]
- Thrombocytopenia [NCIt concept]
- Unfavorable Clinical Outcome [NCIt concept]
Has associated anatomic sites
- Hematopoietic and Lymphatic System [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Blasts Expressing B-Lymphoid and Myeloid Markers Present [NCIt concept]
- Blasts Expressing B-Lymphoid and T-Lymphoid Markers Present [NCIt concept]
- Blasts Expressing B-Lymphoid, T-Lymphoid, and Myeloid Markers Present [NCIt concept]
- Blasts Expressing CD56 and Immature T-Cell Markers Present [NCIt concept]
- Blasts Expressing T-Lymphoid and Myeloid Markers Present [NCIt concept]
- Chronic Clinical Course [NCIt concept]
- Solid Growth Pattern [NCIt concept]
disease_has_abnormal_cell
- Leukemic Cell [NCIt concept]
- Malignant Cell [NCIt concept]
- Neoplastic Blast [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Hematopoietic and Lymphoid Cell [NCIt concept]
disease_has_finding
- Blasts Expressing T-Lymphoid and Megakaryocytic Markers Present [NCIt concept]
- Blasts of Mixed Phenotype Present [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
disease_has_normal_cell_origin
- Hematopoietic and Lymphoid Cell [NCIt concept]
- Multipotent Bone Marrow Stem Cell [NCIt concept]
disease_has_normal_tissue_origin
- Hematopoietic and Lymphoid Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Bone Marrow [NCIt concept]
- Hematopoietic and Lymphatic System [NCIt concept]
disease_may_have_associated_disease
- Anemia [NCIt concept]

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