CUBN wt Allele

Preferred Label : CUBN wt Allele;

NCIt synonyms : IFCR; IGS; Cubilin wt Allele; Cubilin (Intrinsic Factor-Cobalamin Receptor) Gene; IGS1; FSGS9; gp280; MGA1;

NCIt definition : Human CUBN wild-type allele is located in the vicinity of 10p13 and is approximately 306 kb in length. This allele, which encodes cubilin protein, is involved in binding to intrinsic factor-vitamin B12 complexes. Mutation of the gene is associated with autosomal recessive megaloblastic anemia 1.;

NCI Metathesaurus CUI : CL1907120;

GenBank Accession Number : AF034611;

Details

Origin ID

C200305;

OMIM relation
- Cubilin [OMIM gene]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 10p13 [NCIt concept]
gene_plays_role_in_process
- Calcium Binding [NCIt concept]
- Intermediary Metabolic Process [NCIt concept]
- Ion Transport Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Mediated Endocytosis [NCIt concept]
- Receptor Signaling [NCIt concept]
- Transport Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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