Preferred Label : Topical Nigella sativa Seed Oil;
NCIt synonyms : Topical Black Seed Oil; Topical N. sativa Seed Oil;
NCIt definition : A topical preparation containing the oil extracted from the seeds of Nigella sativa,
also known as black seed or black cumin, with potential antioxidant, anti-inflammatory
and immunomodulatory activities. Upon topical administration of Nigella sativa seed
oil, the main constituent thymoquinone may stimulate various cytoprotective antioxidant
enzymes. Thymoquinone may also exert anti-inflammatory activity by decreasing the
production of inflammation mediators, such as tumor necrosis factor (TNF)-alpha, interleukin
(IL) 1-beta and IL-6, and inhibiting pro-inflammatory enzymes, including cyclooxygenase
(COX). In addition, thymoquinone may modulate the activity of various immune cells
such as T-cells, B-cells, macrophages, neutrophils, natural killer (NK) cells, and
dendritic cells (DCs). This may decrease the wound healing process time and may reduce
radiation dermatitis upon radiation therapy.;
NCI Metathesaurus CUI : CL1907046;
Origin ID : C200210;
UMLS CUI : C5856165;
Semantic type(s)
- concept_is_in_subset
