Preferred Label : HBV mRNA Vaccine;
NCIt synonyms : Hepatitis B Virus mRNA Vaccine;
NCIt definition : A vaccine consisting of a mRNA delivery vector encapsulating messenger RNA (mRNA)
encoding an unspecified antigen of hepatitis B virus (HBV), with potential immunomodulating
and antineoplastic activities. Upon administration of the HBV mRNA vaccine, the mRNA
delivery vector releases HBV mRNA into the cells. The mRNA is then translated by the
cellular protein translation machinery to produce the HBV antigen. This results in
the induction of antigen-specific CD8 and CD4 T-cell responses against the HBV antigen.
HBV infection is present in many hepatocellular carcinoma patients.;
NCI Metathesaurus CUI : CL1906961;
Origin ID : C200119;
UMLS CUI : C5856111;
Semantic type(s)
- concept_is_in_subset
