Peripheral T-Cell Lymphoma-GATA3

Preferred Label : Peripheral T-Cell Lymphoma-GATA3;

NCIt synonyms : PTCL-GATA3;

NCIt definition : A molecular subtype of peripheral T-cell lymphoma, not otherwise specified, characterized by high expression of GATA3. It is composed of a monomorphic lymphocytic infiltrate with minimal inflammation and is associated with a poor prognosis.;

Neoplastic status : Malignant;

NCI Metathesaurus CUI : CL1907349;

Details

Origin ID

C200073;

UMLS CUI

C5854280;

Disease excludes abnormal cell
- Lymphocyte Predominant Cell [NCIt concept]
- Neoplastic B-Lymphocyte [NCIt concept]
- Reed-Sternberg Cell [NCIt concept]
Disease excludes normal cell origin
- Myeloid Cell [NCIt concept]
- Plasma Cell [NCIt concept]
- Precursor Natural Killer Cell [NCIt concept]
- Precursor T-Lymphoblast [NCIt concept]
Has associated anatomic sites
- Hematopoietic and Lymphatic System [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Neoplastic Cells with TFH Cell Phenotype Present [NCIt concept]
disease_has_abnormal_cell
- Abnormal Lymphocyte [NCIt concept]
- Malignant Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Hematopoietic and Lymphoid Cell [NCIt concept]
- Neoplastic Lymphocyte [NCIt concept]
- Neoplastic T-Lymphocyte [NCIt concept]
- Neoplastic T-Lymphocyte and Neoplastic Natural Killer Cell [NCIt concept]
disease_has_finding
- GATA3 Overexpression Positive [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Monomorphic Cellular Infiltrate [NCIt concept]
- Not Otherwise Specified Lesion [NCIt concept]
- Unfavorable Clinical Outcome [NCIt concept]
disease_has_normal_cell_origin
- Hematopoietic and Lymphoid Cell [NCIt concept]
- Lymphocyte [NCIt concept]
- Peripheral (Post-Thymic) T-Lymphocyte [NCIt concept]
- Peripheral (Post-Thymic) T-Lymphocyte and Natural Killer Cell [NCIt concept]
- T-Lymphocyte and Natural Killer Cell [NCIt concept]
disease_has_normal_tissue_origin
- Hematopoietic and Lymphoid Tissue [NCIt concept]
- Lymphoid Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Hematopoietic and Lymphatic System [NCIt concept]
- Lymphatic System [NCIt concept]
disease_may_have_molecular_abnormality
- Clonal T-Cell Receptor Beta Chain Gene Rearrangement [NCIt concept]
- Clonal T-Cell Receptor Gamma Chain Gene Rearrangement [NCIt concept]

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