DUSP22-R Anaplastic Large Cell Lymphoma, ALK-Negative

Preferred Label : DUSP22-R Anaplastic Large Cell Lymphoma, ALK-Negative;

NCIt synonyms : DUSP22 Rearranged ALCL, ALK-Negative; DUSP22-R ALCL, ALK-Negative; DUSP22 Rearranged Anaplastic Large Cell Lymphoma, ALK-Negative;

NCIt definition : A genetic subtype of systemic anaplastic large cell lymphoma, ALK-negative characterized by rearrangement of DUSP22 gene. It tends to have a favorable prognosis.;

Neoplastic status : Malignant;

NCI Metathesaurus CUI : CL1907327;

Details

Origin ID

C200050;

UMLS CUI

C5856065;

Disease excludes abnormal cell
- Lymphocyte Predominant Cell [NCIt concept]
- Neoplastic B-Lymphocyte [NCIt concept]
- Reed-Sternberg Cell [NCIt concept]
Disease excludes normal cell origin
- Myeloid Cell [NCIt concept]
- Plasma Cell [NCIt concept]
- Precursor Natural Killer Cell [NCIt concept]
- Precursor T-Lymphoblast [NCIt concept]
Disease may have findings
- Aggressive Clinical Course [NCIt concept]
- Extranodal Disease [NCIt concept]
- Lymphadenopathy [NCIt concept]
Has associated anatomic sites
- Hematopoietic and Lymphatic System [NCIt concept]
Has cytogenetic abnormalities
- DUSP22 Gene Rearrangement [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
disease_excludes_molecular_abnormality
- ALK Fusion Protein Expression [NCIt concept]
disease_has_abnormal_cell
- Abnormal Lymphocyte [NCIt concept]
- Anaplastic Large T-Lymphocyte [NCIt concept]
- Malignant Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Hematopoietic and Lymphoid Cell [NCIt concept]
- Neoplastic Lymphocyte [NCIt concept]
- Neoplastic T-Lymphocyte and Neoplastic Natural Killer Cell [NCIt concept]
disease_has_finding
- Anaplastic Lesion [NCIt concept]
- CD30-Positive Neoplastic Cells Present [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Primary Lesion [NCIt concept]
- Systemic Disease [NCIt concept]
disease_has_normal_cell_origin
- Activated Mature Cytotoxic T-Lymphocyte [NCIt concept]
- Hematopoietic and Lymphoid Cell [NCIt concept]
- Lymphocyte [NCIt concept]
- Mature T-Lymphocyte [NCIt concept]
- Peripheral (Post-Thymic) T-Lymphocyte and Natural Killer Cell [NCIt concept]
- T-Lymphocyte and Natural Killer Cell [NCIt concept]
disease_has_normal_tissue_origin
- Hematopoietic and Lymphoid Tissue [NCIt concept]
- Lymphoid Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Hematopoietic and Lymphatic System [NCIt concept]
- Lymphatic System [NCIt concept]
disease_mapped_to_gene
- DUSP22 Gene [NCIt concept]
disease_may_have_molecular_abnormality
- Clonal T-Cell Receptor Beta Chain Gene Rearrangement [NCIt concept]
- Clonal T-Cell Receptor Gamma Chain Gene Rearrangement [NCIt concept]
pathogenesis_of_disease_involves_gene
- DUSP22 Gene [NCIt concept]
- DUSP22 wt Allele [NCIt concept]

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