NCIt definition : A clonal B-cell lymphoproliferative disease of the bone marrow that results in autoimmune
hemolytic anemia. It is distinct from lymphoplasmacytic lymphoma and IgM monoclonal
gammopathy of undetermined significance. It lacks MYD88 gene mutation and is associated
with trisomies of chromosomes 3, 12, and 18, and mutations in KMT2D and CARD11 genes.;