IgM Monoclonal Gammopathy of Undetermined Significance, Not Otherwise Specified

Preferred Label : IgM Monoclonal Gammopathy of Undetermined Significance, Not Otherwise Specified;

NCIt synonyms : IgM MGUS, NOS; IgM Monoclonal Gammopathy of Undetermined Significance, NOS; IgM MGUS, Not Otherwise Specified;

NCIt definition : A subtype of IgM monoclonal gammopathy of undetermined significance that includes cases associated with MYD88 mutation and cases associated with the presence of monoclonal B-lymphocytes without the presence of abnormal lymphoplasmacytic aggregates that are diagnostic of lymphoplasmacytic lymphoma or other small B-lymphocytic neoplasms.;

Neoplastic status : Undetermined;

NCI Metathesaurus CUI : CL1906766;

Details

Origin ID

C199384;

Disease excludes abnormal cell
- Neoplastic Plasma Cell [NCIt concept]
- Neoplastic T-Lymphocyte and Neoplastic Natural Killer Cell [NCIt concept]
Disease excludes normal cell origin
- Myeloid Cell [NCIt concept]
- Precursor B-Lymphoblast [NCIt concept]
Has associated anatomic sites
- Hematopoietic System [NCIt concept]
- Hematopoietic and Lymphatic System [NCIt concept]
disease_excludes_finding
- Aberrant Clonal Plasma Cell Population [NCIt concept]
- Constitutional Symptom [NCIt concept]
- Hepatosplenomegaly [NCIt concept]
- Lymphadenopathy [NCIt concept]
disease_has_abnormal_cell
- Abnormal Lymphocyte [NCIt concept]
- Neoplastic B-Lymphocyte [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Hematopoietic and Lymphoid Cell [NCIt concept]
- Neoplastic Lymphocyte [NCIt concept]
disease_has_finding
- Bone Marrow Lymphoplasmacytic Infiltration of Less than 10% [NCIt concept]
- Monoclonal Gammopathy [NCIt concept]
- Serum IgM Monoclonal Gammopathy of Less than 30g/L [NCIt concept]
disease_has_normal_cell_origin
- B-Lymphocyte [NCIt concept]
- Hematopoietic and Lymphoid Cell [NCIt concept]
- Lymphocyte [NCIt concept]
- Mature B-Lymphocyte [NCIt concept]
disease_has_normal_tissue_origin
- Hematopoietic and Lymphoid Tissue [NCIt concept]
- Lymphoid Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Hematopoietic and Lymphatic System [NCIt concept]
- Lymphatic System [NCIt concept]
disease_may_have_molecular_abnormality
- MYD88 Gene Mutation [NCIt concept]

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