UBTF/ATXN7L3 Fusion Gene

Preferred Label : UBTF/ATXN7L3 Fusion Gene;

NCIt synonyms : UBTF-ATXN7L3 Fusion Gene; UBTF::ATXN7L3 Fusion Gene;

NCIt definition : A fusion gene resulting from a microdeletion within 17q21.31 that fuses exon 17 of the UBTF gene with a 5' UTR splice site of the ATXN7L3 gene. This chromosomal aberration is associated with certain types of B-acute lymphoblastic leukemia.;

NCI Metathesaurus CUI : CL1906241;

PubMed : 35316324; 35192684; 35397658;

Details

Origin ID

C199304;

gene_encodes_gene_product
- UBTF/ATXN7L3 Fusion Protein [NCIt concept]
gene_involved_in_molecular_abnormality
- UBTF-ATXN7L3 Fusion Protein Expression [NCIt concept]
gene_involved_in_pathogenesis_of_disease
- B Acute Lymphoblastic Leukemia with UBTF-ATXN7L3/PAN3, CDX2 (CDX2/UBTF) [NCIt concept]
gene_mapped_to_disease
- B Acute Lymphoblastic Leukemia with UBTF-ATXN7L3/PAN3, CDX2 (CDX2/UBTF) [NCIt concept]
related_to_genetic_biomarker
- ATXN7L3 Gene [NCIt concept]
- UBTF Gene [NCIt concept]

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