NCIt synonyms : SGF11; Ataxin 7 Like 3 wt Allele; SGF11, S. cerevisiae, Homolog of Gene; Ataxin 7-Like 3 Gene; DKFZp761G2113;
NCIt definition : Human ATXN7L3 wild-type allele is located in the vicinity of 17q21.31 and is approximately
8 kb in length. This allele, which encodes ataxin-7-like protein 3, plays a role in
the deubiquitination of monoubiquitinated histones. Fusions involving this gene and
the UBTF gene resulting from microdeletions within 17q21.31 are associated with B-cell
acute lymphoblastic lymphoma and a fusion of this gene and the GPATCH8 gene may be
associated with diffuse large B cell lymphoma.;
OMIM relation