ZNF362 wt Allele

Preferred Label : ZNF362 wt Allele;

NCIt synonyms : FLJ25476; Rotund Homolog (Drosophila) Gene; Zinc Finger Protein 362 wt Allele; RN; PP6997; lin-29; Rotund Homolog Gene;

NCIt definition : Human ZNF362 wild-type allele is located in the vicinity 1p35.1 and is approximately 173 kb in length. This allele, which encodes zinc finger protein 362, may play a role in transcriptional regulation. A chromosomal translocation, t(1;9)(p35;p24), involving this gene and the SMARCA2 gene may be associated with B-cell acute lymphoblastic leukemia and rearrangements with breakpoints in the vicinity of this gene (1p35.1) and the vicinity of the FOXJ3 gene (1p34.2) may be associated with breast cancers and other solid tumors.;

NCI Metathesaurus CUI : CL1906179;

GenBank Accession Number : NM_152493;

Details

Origin ID

C199244;

UMLS CUI

C5849046;

Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_involved_in_pathogenesis_of_disease
- B Acute Lymphoblastic Leukemia with ZNF362 Rearrangement [NCIt concept]
gene_plays_role_in_process
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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