" /> Elritercept - CISMeF





Preferred Label : Elritercept;

NCIt synonyms : Activin Type 2A Receptor Fc Fusion Protein KER-050; Activin Type IIA Receptor Fc Fusion Protein KER-050;

NCIt definition : A recombinant fusion protein composed of a modified form of the ligand-binding domain of the human transforming growth factor beta (TGF-b) receptor activin receptor type IIA (ActRIIA) and linked to the Fc domain of human antibody, with red blood cell (RBC) and platelet stimulating activities. Upon subcutaneous administration, elritercept acts as a ligand trap, and binds to a subset of the TGF-b family of proteins. This inhibits the binding of these proteins to their receptors and blocks signaling mediated by this subset of TGF-b family of proteins and their receptors. This may promote hematopoiesis and increase RBC and platelet production.;

UNII : ZNC37E4KAK;

CAS number : 2727114-26-1;

Molecule name : KER 050; KER-050;

NCI Metathesaurus CUI : CL1906148;

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14/07/2025


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