Preferred Label : Ventana ALK D5F3;
NCIt synonyms : Ventana ALK (D5F3) Assay; Ventana ALK (D5F3) Companion Diagnostic Assay; Ventana ALK (D5F3) CDx Assay;
NCIt definition : A proprietary immunohistochemistry-based assay used to detect the anaplastic lymphoma
kinase (ALK) protein. It uses rabbit monoclonal antibody D5F3 to specifically bind
ALK and ALK-fusion proteins expressed by tumor cells in formalin-fixed, paraffin-embedded
(FFPE) specimens. This assay may be used to determine if subjects are eligible for
treatment with ALK-targeted tyrosine kinase inhibitors (TKI).;
NCI Metathesaurus CUI : CL1906133;
Origin ID : C199183;
UMLS CUI : C5855438;
Semantic type(s)
- related_to_genetic_biomarker
