IRF2BP2/RARA Fusion Gene

Preferred Label : IRF2BP2/RARA Fusion Gene;

NCIt synonyms : IRF2BP2-RARA Fusion Gene; IRF2BP2::RARA Fusion Gene;

NCIt definition : A fusion gene resulting from a chromosomal translocation, t(1;17)(q42.3;q21.2), which fuses exon 1, exon 1b or exon 2 of the IRF2BP2 gene with exon 3 of the RARA gene. This chromosomal aberration is associated with acute myeloid leukemia with a variant RARA translocation.;

NCI Metathesaurus CUI : CL1906300;

Details

Origin ID

C198855;

gene_encodes_gene_product
- IRF2BP2/RARA Fusion Protein [NCIt concept]
gene_has_abnormality
- t(1;17)(q42.3;q21.2) [NCIt concept]
gene_involved_in_molecular_abnormality
- IRF2BP2-RARA Fusion Protein Expression [NCIt concept]
- t(1;17)(q42.3;q21.2) [NCIt concept]
gene_involved_in_pathogenesis_of_disease
- Acute Myeloid Leukemia with t(1;17)(q42.3;q21.2); IRF2BP2-RARA [NCIt concept]
gene_mapped_to_disease
- Acute Myeloid Leukemia with t(1;17)(q42.3;q21.2); IRF2BP2-RARA [NCIt concept]
related_to_genetic_biomarker
- IRF2BP2 Gene [NCIt concept]
- RARA Gene [NCIt concept]

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