Noonan Syndrome-Associated Myeloproliferative Disorder

Preferred Label : Noonan Syndrome-Associated Myeloproliferative Disorder;

NCIt definition : A transient myeloproliferative disorder that is associated with Noonan syndrome and occurs in the first year of life. It is associated with germline mutations in PTPN11, KRAS, NRAS, or RIT1 genes.;

Neoplastic status : Undetermined;

NCI Metathesaurus CUI : CL1905824;

Details

Origin ID

C198662;

Has associated anatomic sites
- Hematopoietic and Lymphatic System [NCIt concept]
disease_has_abnormal_cell
- Neoplastic Cell [NCIt concept]
- Neoplastic Hematopoietic and Lymphoid Cell [NCIt concept]
- Neoplastic Myeloid Cell [NCIt concept]
disease_has_associated_disease
- Noonan Syndrome [NCIt concept]
disease_has_finding
- Childhood Lesion [NCIt concept]
disease_has_molecular_abnormality
- Germline Variation [NCIt concept]
disease_has_normal_cell_origin
- Bone Marrow Stem Cell [NCIt concept]
- Hematopoietic and Lymphoid Cell [NCIt concept]
- Myeloid Cell [NCIt concept]
disease_has_normal_tissue_origin
- Hematopoietic Tissue [NCIt concept]
- Hematopoietic and Lymphoid Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Bone Marrow [NCIt concept]
- Hematopoietic and Lymphatic System [NCIt concept]
disease_may_have_molecular_abnormality
- KRAS Gene Mutation [NCIt concept]
- NRAS Gene Mutation [NCIt concept]
- PTPN11 Gene Mutation [NCIt concept]
- RIT1 Gene Mutation [NCIt concept]

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