Acute Myeloid Leukemia with Mutated TP53

Preferred Label : Acute Myeloid Leukemia with Mutated TP53;

NCIt synonyms : AML with Mutated TP53;

NCIt definition : Acute myeloid leukemia characterized by the presence of TP53 gene mutations. There are 20% or more blasts in bone marrow or peripheral blood.;

Neoplastic status : Malignant;

NCI Metathesaurus CUI : CL1905769;

Details

Origin ID

C198596;

Disease excludes abnormal cell
- Neoplastic Lymphoblast [NCIt concept]
Disease excludes normal cell origin
- Lymphocyte [NCIt concept]
Has associated anatomic sites
- Bone Marrow [NCIt concept]
- Hematopoietic and Lymphatic System [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Chronic Clinical Course [NCIt concept]
- Solid Growth Pattern [NCIt concept]
disease_has_abnormal_cell
- Leukemic Cell [NCIt concept]
- Malignant Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Hematopoietic and Lymphoid Cell [NCIt concept]
- Neoplastic Myeloblast [NCIt concept]
- Neoplastic Myeloid Cell [NCIt concept]
disease_has_finding
- Blasts 20 Percent or More of Bone Marrow Nucleated Cells [NCIt concept]
- Blasts 20 Percent or More of Peripheral Blood White Cells [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
disease_has_molecular_abnormality
- TP53 Gene Mutation [NCIt concept]
disease_has_normal_cell_origin
- Bone Marrow Stem Cell [NCIt concept]
- Hematopoietic and Lymphoid Cell [NCIt concept]
disease_has_normal_tissue_origin
- Hematopoietic Tissue [NCIt concept]
- Hematopoietic and Lymphoid Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Bone Marrow [NCIt concept]
- Hematopoietic and Lymphatic System [NCIt concept]
disease_mapped_to_gene
- TP53 Gene [NCIt concept]

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