NCIt synonyms : FLJ22422; Cyclin O wt Allele; UDG2; Cyclin U Gene; UNG2; CILD29; CCNU;
NCIt definition : Human CCNO wild-type allele is located in the vicinity of 5q11.2 and is approximately
2 kb in length. This allele, which encodes cyclin-O protein, is involved in centriole
amplification and ciliogenesis. Mutation of the gene is associated with primary ciliary
dyskinesia type 29.;
NCIt note : The CCNO gene product was originally thought to encode a protein with uracil-DNA glycosylase
(UDG) activity and assigned the synonyms UNG2 and UDG2. It was later determined that
this gene product does not exhibit UDG activity and it was confirmed to be a member
of the cyclin family. (from UniProt);