Childhood Acute Lymphoblastic Leukemia CNS 3 Toronto Guidelines v2

Preferred Label : Childhood Acute Lymphoblastic Leukemia CNS 3 Toronto Guidelines v2;

NCIt synonyms : Childhood Acute Lymphoblastic Leukemia Central Nervous System 3 Toronto Guidelines v2; Pediatric Acute Lymphoblastic Leukemia Central Nervous System 3 Toronto Guidelines v2; Pediatric Acute Lymphoblastic Leukemia CNS 3 Toronto Guidelines v2;

NCIt related terms : Acute lymphoblastic leukemia CNS3;

NCIt definition : Clinical signs of CNS involvement or blasts in CSF and WBC or 5/uL CSF and either: RBC 10/uL CSF or RBC or 10/uL CSF and WBC/RBC in CSF 2x WBC/RBC in blood. (Childhood cancer staging for population registries according to the Toronto Childhood Cancer Stage Guidelines - Version 2. Cancer Council Queensland and Cancer Australia: Brisbane, Australia; 2021.);

Neoplastic status : Malignant;

NCI Metathesaurus CUI : CL1913782;

Details

Origin ID

C198040;

UMLS CUI

C5786742;

Disease excludes abnormal cell
- Leukemic Plasma Cell [NCIt concept]
Disease excludes normal cell origin
- Myeloid Cell [NCIt concept]
Disease may have findings
- Hepatomegaly [NCIt concept]
- Lymphadenopathy [NCIt concept]
Has associated anatomic sites
- Hematopoietic and Lymphatic System [NCIt concept]
Semantic type(s)
- Classification [UMLS semantic type]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Chronic Clinical Course [NCIt concept]
- Solid Growth Pattern [NCIt concept]
disease_has_abnormal_cell
- Abnormal Lymphocyte [NCIt concept]
- Leukemic Cell [NCIt concept]
- Leukemic Lymphocyte [NCIt concept]
- Malignant Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Hematopoietic and Lymphoid Cell [NCIt concept]
- Neoplastic Lymphoblast [NCIt concept]
- Neoplastic Lymphocyte [NCIt concept]
disease_has_finding
- Blasts Present in Cerebrospinal Fluid with Clinical Signs of Central Nervous System Involvement [NCIt concept]
- Childhood Lesion [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
disease_has_normal_cell_origin
- Hematopoietic and Lymphoid Cell [NCIt concept]
- Lymphoblast [NCIt concept]
- Lymphocyte [NCIt concept]
disease_has_normal_tissue_origin
- Hematopoietic and Lymphoid Tissue [NCIt concept]
- Lymphoid Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Bone Marrow [NCIt concept]
- Hematopoietic and Lymphatic System [NCIt concept]
- Lymphatic System [NCIt concept]
disease_is_stage
- Toronto Classification v2 Stage [NCIt concept]
- Toronto Classification v2 Stage, Tier 2 [NCIt concept]
disease_may_have_molecular_abnormality
- Clonal T-Cell Receptor Beta Chain Gene Rearrangement [NCIt concept]
- Clonal T-Cell Receptor Gamma Chain Gene Rearrangement [NCIt concept]

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