Preferred Label : Childhood Cancer Stage by Toronto Guidelines v2;
NCIt synonyms : Pediatric Cancer Stage by Toronto Guidelines v2;
NCIt definition : A term that refers to the staging of childhood cancers following the rules of the
Toronto guidelines v2, 2019. The guidelines were developed to address the lack of
consistent information on childhood cancer staging in population registries and are
not intended to replace staging systems in clinical use. They include a two-tiered
approach that provides less detailed criteria for registries with limited resources
and/or limited data access (Tier 1) and more detailed criteria for better-resourced
registries (Tier 2). They apply to acute lymphoblastic leukemia, Hodgkin lymphoma,
non-Hodgkin lymphoma, neuroblastoma, renal malignant tumors except renal cell carcinoma,
rhabdomyosarcoma, non-rhabdomyosarcoma soft tissue sarcoma, malignant bone tumors,
retinoblastoma, hepatoblastoma, testicular germ cell tumors, ovarian germ cell tumors,
astrocytoma, medulloblastoma and ependymoma. The following changes were noted to the
original classification (v1, 2014): a staging system was no longer considered appropriate
for acute myeloid leukemia; all renal tumors, with the exception of renal cell carcinomas,
should use the endorsed staging systems for Wilms tumor; staging systems for osteosarcoma
and Ewing sarcoma were combined into a single recommendation for all malignant bone
tumors; a staging system was endorsed for astrocytomas; the S category (serum tumor
markers) was confirmed as an integral part of TNM staging for testicular cancer in
Tier 2 recommendations; and PRETEXT number was added to Tier 2 recommendations for
hepatoblastoma. (adapted from Childhood cancer staging for population registries according
to the Toronto Childhood Cancer Stage Guidelines - Version 2. Cancer Council Queensland
and Cancer Australia: Brisbane, Australia; 2021.);
Neoplastic status : Malignant;
NCI Metathesaurus CUI : CL1913808;
Origin ID : C198027;
UMLS CUI : C5786730;
Semantic type(s)
- disease_excludes_finding
- disease_has_abnormal_cell
- disease_has_finding
- disease_is_stage
